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HPK1-IN-3 Catalog No.:M16248-C NB-598 is a potent competitive

SKU: 65466158824

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Description

NB-598 is a potent competitive inhibitor of squalene epoxidase (SE)

Proteasome inhibitors: recent advances and new perspectives in medicinal chemistry

Chemical Name: 6-nitro-1-benzothiophene-1

Chemical Name: N-{2-[2-(4-chlorophenyl)-1

InChiKey: IZPMWFSVTDOCDI-HAVVHWLPSA-N

HPK1-IN-3 Catalog No.:M16248-C NB-598 is a potent competitiveHPK1 IN 3 is a potent and selective ATP competitive hematopoietic progenitor kinase 1 (HPK1; MAP4K1) inhibitor with an IC50 of 0. 25 nM. HPK1 IN 3 has IL 2 cellular potency with an EC50 of 108 nM in human peripheral blood mononuclear cells (PBMCs). Product information Molecular Weight: 490. 45 Formula: C23H22F4N6O2 Chemical Name: 4 ((2 fluoro 6 (trifluoromethyl)phenyl)amino) 2 ((6 methoxy 2 methyl 1, 2, 3, 4 tetrahydroisoquinolin 7 yl)amino)pyrimidine

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