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targeting Smoothened (Smo) with an EC50 ~1 nM
Smiles: C[C@@]12[C@@H]3C(=O)CC[C@]3(CC[C@H]1C)[C@@H](C)[C@H](O)[C@@](C)(C[C@H]2OC(=O)CO)C=C
L002 was used at 5-30 µM final concentration in various in vitro assays
InChi: InChI=1S/C15H10BrNO2/c16-11-7-5-10(6-8-11)9-17-13-4-2-1-3-12(13)14(18)15(17)19/h1-8H
In primary cultures of rat cerebrocortical neurons
Iloperidone Hydrochloride imus targeting Smoothened (Smo) with anIloperidone HCl is a dual D2 5 HT2 antagonist as an antipsychotic agent. Product information CAS Number: 1299470 39 5 Molecular Weight: 462. 94 Formula: C24H28ClFN2O4 Chemical Name: 1 (4 {3 [4 (6 fluoro 1,2 benzoxazol 3 yl)piperidin 1 yl]propoxy} 3 methoxyphenyl)ethan 1 one hydrochloride Smiles: Cl. CC(=O)C1=CC(OC)=C(C=C1)OCCCN1CCC(CC1)C1=NOC2=CC(F)=CC=C21 InChiKey: FGACDTCLJARDGD UHFFFAOYSA N InChi: InChI=1S C24H27FN2O4. ClH c1 16(28)18 4 7 21(23(14
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