Pay in 4 interest-free payments of $13.75 Learn more
Ships within 48 hours · Estimated delivery Aug 19 - Aug 24
Phase I study of TAS-102 and irinotecan combination therapy in Japanese patients with advanced colorectal cancer
CAS Number: 1446321-46-5
It is a good chemical tool to enable interrogation of GPR39 signaling in different cellular contexts
1 mg/kg (p
biochemically
Spautin-1 - Autophagy Inhibitor. CAS# 1262888-28-7 Catalog No.:M60003-10S Phase I study of TAS-102Spautin 1, CAS No. 1262888 28 7, is a potent autophagy inhibitor with an IC50 ~0. 74 M, and was discovered by an imaging based screen. It can selectively promote the degradation of Vps34 complexes. Mechanistic studies showed that Spautin 1 inhibited two ubiquitin specific peptidases, USP10 and USP13, which target the Beclin1 subunit of Vps34 complexes. Since USP10 mediates the deubiquitination of p53, regulating deubiquitination activity of USP10 and
US$ 32.00
US$ 40.00
US$ 115.00
US$ 18.00
US$ 18.00
US$ 105.00
US$ 45.00
US$ 10.00
US$ 55.00