CZC-25146 Hydrochloride 64 2HCl 13-Acetyl-9-dihydrobaccatin III

13-Acetyl-9-dihydrobaccatin III

2-trifluoro-1-(4-fluorophenyl)ethyl]amino}propanamido]-2-oxopentanamide

Formula: C19H31N5O2

ClH/c1-3-21-8-11(17(24)25)16(23)10-6-12(18)15(13(19)14(10)21)22-5-4-20-9(2)7-22

UK-92480 increases connexin 40 in smooth muscle cells through activation of BMP pathways in pulmonary arterial hypertension

CZC-25146 Hydrochloride 64 2HCl 13-Acetyl-9-dihydrobaccatin IIICZC 25146 is a potent and selective LRRK2 inhibitor. Leucine rich repeat kinase 2 (LRRK2) mutations are the most important cause of familial Parkinson's disease. CZC 25146 prevents mutant LRRK2 induced injury of cultured rodent and human neurons with mid nanomolar potency. Product information CAS Number: 1330003 04 7 Molecular Weight: 525. 00 Formula: C22H26ClFN6O4S Chemical Name: N {2 [(5 fluoro 2 {[2 methoxy 4 (morpholin 4 yl)phenyl]amino}pyrimidin