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Ivacaftor (benzenesulfonate) Catalog No.:M9558-2 Chemical Name: 2-diphenylmethanesulfinyl-N-hydroxyacetamide

SKU: 61157789288

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Description

Chemical Name: 2-diphenylmethanesulfinyl-N-hydroxyacetamide

In order to examine the role of PKC in p38MAPK phosphorylation

Activation of human FFA4 by TUG-891 also resulted in rapid phosphorylation and internalization of the receptor

InChi: InChI=1S/C32H36N6O4/c1-22-7-6-8-23(2)30(22)42-32(39)38(27-14-13-26(40-4)21-28(27)41-5)29-15-16-33-31(35-29)34-24-9-11-25(12-10-24)37-19-17-36(3)18-20-37/h6-16

Chemical Name: 2-[(1R

Ivacaftor (benzenesulfonate) Catalog No.:M9558-2 Chemical Name: 2-diphenylmethanesulfinyl-N-hydroxyacetamideVX 770, is a drug used to treat cystic fibrosis in people with certain mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, who account for 45% cases of cystic fibrosis, and is included in a combination drug, lumacaftor ivacaftor, which is used to treat people with cystic fibrosis who have the F508del mutation in CFTR. Ivacaftor is a "potentiator" of CFTR, meaning it increases the probability that the defective channel

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