SMN-C3 vir hydrate AEE788 (50 mg/kg) also inhibits

AEE788 (50 mg/kg) also inhibits growth of tumors in the cecum and peritoneum (>50%) and reduces the incidence of lymph node metastasis to 70% in HT29 cells implanted in the cecum of nude mice

Purpurogallin (100 µM

9(9):1180-6

CAS Number: 1202402-40-1

1021/tx200525n

SMN-C3 vir hydrate AEE788 (50 mg/kg) also inhibitsSMN C3 is an orally active SMN2 splicing modulator and has the potential to treat spinal muscular atrophy (SMA). Product information CAS Number: 1449597 34 5 Molecular Weight: 416. 52 Formula: C24H28N6O Chemical Name: 2 {4,6 dimethylpyrazolo[1,5 a]pyrazin 2 yl} 7 (1 ethylpiperidin 4 yl) 9 methyl 4H pyrido[1,2 a]pyrimidin 4 one Smiles: CCN1CCC(CC1)C1=CN2C(=O)C=C(N=C2C(C)=C1)C1C=C2C(C)=NC(C)=CN2N=1 InChiKey: ZACWYYKZMLGOTG UHFFFAOYSA N InChi: InChI=1S