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proteinase 3
]nonan-9-ium-9-olate hydrobromide
18 nM (1 ng/mL)
InChi: InChI=1S/C31H41N7O6/c1-19(2)15-24(27(40)34-22(18-39)16-20-9-5-3-6-10-20)35-28(41)26(23-13-14-33-30(32)36-23)38-31(44)37-25(29(42)43)17-21-11-7-4-8-12-21/h3-12
1-3H3/b15-11+
Jatrorrhizine hydroxide 6 tetrasodium salt proteinase 3Jatrorrhizine hydroxide is an alkaloid isolated from Coptis chinensis with neuroprotective, antimicrobial, antiplasmodial and antioxidant activities. Jatrorrhizine hydroxide is a potent and orally active inhibitor of AChE (IC50=872 nM) over >115 fold selectivity for BuChE. Jatrorrhizine hydroxide reduces uptake of serotonin (5 HT) and norepinephrine (NE) via inhibition of uptake 2 transporters. Product information CAS Number: 483 43 2 Molecular
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