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Molecular Weight: 852
CC(=O)OC1=CC2CN(CCC=2S1)C(C1=CC=CC=C1F)C(=O)C1CC1
Smiles: CC(C)(C)NCC(O)C1C=C(O)C=C(O)C=1
InChiKey: ITRJWOMZKQRYTA-RFZYENFJSA-N
noncardiotoxic aza-anthracenedione analogue with potential antineoplastic activity
Refametinib (R) 0531 Molecular Weight: 852Refametinib R enantiomer is a potent, selective and allosteric inhibitor of MEK1 2 in enzyme inhibition assays. Refametinib R has been reported to inhibit MEK activity and inhibit anchorage dependent growth. Moreover, it has shown a potent tumor growth inhibition (TGI) in the human A375 and colon carcinoma Colo205 tumor xenograft models. Product information CAS Number: 923032 38 6 Molecular Weight: 572. 34 Formula: C19H20F3IN2O5S Synonym: BAY 869766 R
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