YM-201636 - CAS# 371942-69-7 size:2mg solid selective and cell permeable inhibitor

selective and cell permeable inhibitor of the homologous protein lysine methyltransferases

Stock Solution Storage: -80°C for 6 months -20°C for 1 month

CAS Number: 1044870-39-4

It is completely inactive against type II and type III PRMTs

and induces caspase-dependent apoptosis by 24% at 1 μM

YM-201636 - CAS# 371942-69-7 size:2mg solid selective and cell permeable inhibitorYM 201636, CAS No. 371942 69 7, is an inhibitor of retroviral budding and PIKfyve catalyzed PtdIns(3, 5)P2 synthesis, and can also halt glucose entry by insulin in adipocytes. YM 201636 almost completely inhibited basal and insulin activated 2 deoxyglucose uptake at doses as low as 160 nM, with IC(50)=54+ 4 nM for the net insulin response. Insulin induced GLUT4 translocation was partially inhibited at substantially higher doses, comparable to those