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Smiles: COC1=CC(=CC=C1C(O)=O)NC1=NC2=C(CN=C(C3=C(F)C=CC=C3OC)C3=CC(Cl)=CC=C32)C=N1
1021/jm5014055
The second class of binding sites is more sensitive to PD-123319
is a potent and selective inhibitor of NUAK1 (IC50 = 100 nM) and does not affect the activity of a panel of 139 other kinases
CAS Number: 924416-43-3
Hydroxy-Fasudil - CAS# 105628-72-6 sporin C sodium Smiles: COC1=CC(=CC=C1C(O)=O)NC1=NC2=C(CN=C(C3=C(F)C=CC=C3OC)C3=CC(Cl)=CC=C32)C=N1Hydroxy Fasudil, a potent Rho kinase inhibitor and vasodilator, CAS No. 105628 72 6, is a metabolite of Fasudil, acting as a potent Rho kinase inhibitor and vasodilator. Product information CAS Number: 105628 72 6 Molecular Weight: 307. 37 Formula: C14H17N3O3S Synonym: Hydroxy Fasudil Chemical Name: 5 (1,4 diazepan 1 ylsulfonyl) 2H isoquinolin 1 one Smiles: O=C1NC=CC2=C1C=CC=C2S(=O)(=O)N1CCCNCC1 InChiKey: ZAVGJDAFCZAWSZ UHFFFAOYSA N InChi: InChI=1S
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