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VRT 752271
Induction of cell death in antiestrogen resistant human breast cancer cells by the protein kinase CK2 inhibitorDMAT
Small-molecule correctors such as KM11060 may serve as useful pharmacological tools in studies of the F508del-CFTR processing defect and in the development of cystic fibrosis therapeutics
Apoptosis Activator 2 is a potent and selective carboxylesterase inhibitor with Ki of 67/31/65 nM for hiCE/hCE/rCE respectively
which is structurally an analogue of naproxen
GSK-2981278 - CAS# 1474110-21-8 Catalog No.:M6485-10 VRT 752271GSK 2981278, CAS No. 1474110 21 8, is a highly potent and selective inverse agonist of retinoic acid receptor related orphan receptor gamma (ROR gamma). GSK 2981278 is a strong ROR selective inverse agonist that inhibits activation of the il17 promoter. GSK 2981278 robustly inhibits ROR mediated cytokine production at both the mRNA and protein level. GSK 2981278 attenuates inflammation in a mouse model of psoriasis. Topical treatment with GSK 2981278
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