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Charles E Mowbray
3-dimethylpropanoyl)oxy]-5a
Shearer TW
Formula: C17H15BrF2N4O3
indicating that it is devoid of CCR5 agonist activity
AP1189 acetate Size:2mg solid Charles E MowbrayAP1189 is a biased agonist at receptors MC1 and MC3. AP1189 reduced cytokine release, an effect reliant on both MC1 and MC3 as evident from the use of Mc1r( ) and Mc3r( ) macrophages. No melanogenesis was induced by AP1189 in B16 F10 melanocytes. In vivo, oral AP1189 elicited anti inflammatory actions in peritonitis and, upon administration at the peak of inflammation, accelerated the resolution phase by 3 fold. Product information CAS Number: 959850
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