N-Desmethyltamoxifen hydrochloride - CAS# 15917-65-4 0273 Smiles: CO[C@H]1[C@H](C[C@@H]2O[C@@]1(C)N1C3C(=C4C(O)NC(=O)C4=C4C=3N2C2=CC=CC=C24)C2=CC=CC=C12)NC

Smiles: CO[C@H]1[C@H](C[C@@H]2O[C@@]1(C)N1C3C(=C4C(O)NC(=O)C4=C4C=3N2C2=CC=CC=C24)C2=CC=CC=C12)NC

2(6):1492-7

prevention of blood-brain barrier opening

1401532-80-6 (SAG(cis）)

SBI-0206965

N-Desmethyltamoxifen hydrochloride - CAS# 15917-65-4 0273 Smiles: CO[C@H]1[C@H](C[C@@H]2O[C@@]1(C)N1C3C(=C4C(O)NC(=O)C4=C4C=3N2C2=CC=CC=C24)C2=CC=CC=C12)NCN Desmethyltamoxifen hydrochloride, CAS No. 15917 65 4, is the major metabolite of tamoxifen in humans. N Desmethyltamoxifen, a poor antiestrogen, is a ten fold more potent protein kinase C (PKC) inhibitor than Tamoxifen. N Desmethyltamoxifen hydrochloride is also a potent regulator of ceramide metabolism in human AML cells, limiting ceramide glycosylation, hydrolysis, and sphingosine phosphorylation. Product information CAS Number: 15917 65 4