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Linifanib (ABT-869) - CAS# 796967-16-3 acin(DU 6859A) 26(2):278-288

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Description

26(2):278-288

[3] Combining Tipifarnib with 10 nM 4-OH-tamoxifen in the presence of E2 reduces the IC50 8-fold from 400 to 50 nM

PMID: 32152610

Go-6976 is a potent inhibitor of PKC in vitro (IC50 is 20 nM

Sachinidis A

Linifanib (ABT-869) - CAS# 796967-16-3 acin(DU 6859A) 26(2):278-288Linifanib, CAS No. 796967 16 3, also known as ABT 869, is an orally bioavailable, small molecule receptor tyrosine kinase (RTK) inhibitor with potential antineoplastic activity. Linifanib inhibits members of the vascular endothelial growth factor (VEGF) and platelet derived growth factor (PDGF) receptor families; it exhibits much less activity against unrelated RTKs, soluble tyrosine kinases, or serine threonine kinases. This agent does not have a

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