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TAK-659 3992 selective and cell-permeable p300/CBP histone

SKU: 53594847752

4.7
USD100.00 USD145.00

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Description

selective and cell-permeable p300/CBP histone acetyltransferase (HAT) inhibitor with an IC50 ~400 nM

PRN694 inhibits TEC

Formula: C18H34O11

and can be used in the treatment of various diseases

InChiKey: GMMOXURYXYPBKB-UHFFFAOYSA-N

TAK-659 3992 selective and cell-permeable p300/CBP histoneTAK 659 is a highly potent, selective, reversible and orally available dual inhibitor of spleen tyrosine kinase (SYK) and fms related tyrosine kinase 3 (FLT3), with an IC50 of 3. 2 nM and 4. 6 nM for SYK and FLT3, respectively. TAK 659 induces cell death in tumor cells but not in nontumor cells, and with potential for the treatment of chronic lymphocytic leukemia (CLL). Product information CAS Number: 1312691 33 0 Molecular Weight: 344. 39 Formula:

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