Pay in 4 interest-free payments of $21.25 Learn more
Ships within 48 hours · Estimated delivery Aug 7 - Aug 12
Formula: C15H10FNO3
Formula: C35H46O20
2020 Feb 18
Gadodiamide injection produces less severe alterations in hemodynamics than gadopentetate dimeglumine
Int J Biochem Cell Biol
TH588 - MTH1 Inhibitor. CAS# 1609960-31-7 Catalog No.:M60211-10S Formula: C15H10FNO3TH588, CAS No. 1609960 31 7, is a novel potent, selective and cell permeable inhibitor of the nudix hydrolase family MTH1 protein with an IC50 of ~5 nM. Protein co crystal structures demonstrate that TH588 binds in the active site of MTH1. It has excellent selectivity over other nudix family proteins and kinases present in the selectivity panel. The MTH1 protein sanitizes oxidized dNTP pools to prevent incorporation of damaged bases during DNA