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11S)-11-hydroxy-9-methyl-3-oxatricyclo[5
H2O/c17-10-6-12(19)11(18)4-8(10)3-9(23)5-14(28)26-1-2-27-13(7-26)24-25-15(27)16(20
Formula: C21H24Cl2FNO2
InChi: InChI=1S/C24H29NO3/c1-27-22-14-19-13-20(24(26)21(19)15-23(22)28-2)12-17-8-10-25(11-9-17)16-18-6-4-3-5-7-18/h3-7
CAS Number: 943344-58-9
GNE-049 at mesylate 11S)-11-hydroxy-9-methyl-3-oxatricyclo[5GNE 049 is a highly potent and selective CBP inhibitor with an IC50 of 1. 1 nM in TR FRET assay. GNE 049 also inhibits BRET and BRD4(1) with IC50s of 12 nM and 4200 nM, respectively. Product information CAS Number: 1936421 41 8 Molecular Weight: 510. 58 Formula: C27H32F2N6O2 Chemical Name: 1 {3 [7 (difluoromethyl) 6 (1 methyl 1H pyrazol 4 yl) 1,2,3,4 tetrahydroquinolin 1 yl] 1 (oxan 4 yl) 1H,4H,5H,6H,7H pyrazolo[4,3 c]pyridin 5 yl}ethan 1 one Smiles:
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