Pay in 4 interest-free payments of $8.00 Learn more
Ships within 48 hours · Estimated delivery Aug 2 - Aug 7
125256-00-0
(2013) Nat Cell Biol
(2008) J Neurosci
919973-83-4
InChi: InChI=1S/C25H30N2O5/c1-15-21(24(29)32-18-7-5-4-6-8-18)22(16-9-11-17(12-10-16)27(30)31)23-19(26-15)13-25(2
MHY1485 - mTOR Activator. CAS# 326914-06-1 Catalog No.:M60189-10S 125256-00-0MHY1485, CAS No. 326914 06 1, is a novel potent, selective and cell permeable mTOR activator. It suppressed the basal autophagic flux, and this inhibitory effect was clearly confirmed in cells under starvation, a strong physiological inducer of autophagy. It can increase cellular mTOR Ser2448 and downstream substrate 4E BP Thr37 46 phosphorylation level in rat liver Ac2F cells (1 to 2 M for 1 h). It affects culture viability only at much higher