N-Acetyl calicheamicin - enediyne antitumor antibiotic. CAS# 108212-76-6 Size:2mg solid N2-[(1S)-1-(4-fluorophenyl)ethyl]-4-(1-methyl-1H-pyrazol-4-yl)-N6-(pyrazin-2-yl)pyridine-2

N2-[(1S)-1-(4-fluorophenyl)ethyl]-4-(1-methyl-1H-pyrazol-4-yl)-N6-(pyrazin-2-yl)pyridine-2

InChiKey: PRMWGUBFXWROHD-UHFFFAOYSA-N

followed by cell growth inhibition and cell death

4-c]pyrazol-5(2H

CAS Number: 524684-52-4

N-Acetyl calicheamicin - enediyne antitumor antibiotic. CAS# 108212-76-6 Size:2mg solid N2-[(1S)-1-(4-fluorophenyl)ethyl]-4-(1-methyl-1H-pyrazol-4-yl)-N6-(pyrazin-2-yl)pyridine-2N Acetyl calicheamicin, CAS No. 108212 76 6, is a derivative of calicheamicin, and is a potent enediyne antitumor antibiotic. Calicheamicins target DNA and cause strand scission. Calicheamicins bind with DNA in the minor groove, wherein they then undergo a reaction analogous to the Bergman cyclization to generate a diradical species. This diradical, 1, 4 didehydrobenzene, then abstracts hydrogen atoms from the deoxyribose (sugar) backbone of DNA,