Lysine-specific Demethylase Inhibitor (1C) orine hydrochloride CAS Number: 732983-37-8

CAS Number: 732983-37-8

Chemical Name: 2-{[5-hydroxy-7-(hydroxymethyl)-1H

3-dihydro-1H-indol-5-yl]ethyl]benzamide

Smiles: COC1=CC2=CC(=CC(=O)C(O)=C2C(O)=C1O)C(=O)OCCCCCC

Smiles: CN1C2C=C(C=CC=2C(C)=CC1=O)N1[C@@H]([C@H](CCC1=O)NS(=O)(=O)CC(C)C)C1C=CC(Cl)=CC=1

Lysine-specific Demethylase Inhibitor (1C) orine hydrochloride CAS Number: 732983-37-8Lysine specific Demethylase Inhibitor (1C) is a lysine specific demethylase inhibitor. Lysine specific demethylase 1 (LSD1) is the first of several protein lysine demethylases identified. Through a FAD dependent oxidative reaction, LSD1 could specifically remove histone H3K4me2 to H3K4me1 or H3K4me0. When forming a complex with androgen receptor, LSD1 alters its substrates to H3K9me2. The LSD1 complex regulates a coordinated histone modification