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UM171 - Human HSC Self-renewal Agonist. size:Contact [email protected] for more infomation Formula: C22H37NO7

SKU: 50973910372

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Description

Formula: C22H37NO7

is repressed by INCB-057643 in human and mouse whole blood stimulated ex vivo with LPS

for analysis

male adult Wistar rats) treatment dose-dependently facilitates penile erection when given s

Formula: C17H14O5

UM171 - Human HSC Self-renewal Agonist. size:Contact [email protected] for more infomation Formula: C22H37NO7UM171, CAS No. 1448724 09 1, is a potent small molecule that stimulates the ex vivo expansion of human hematopoietic stem cells HSC capable of reconstituting human hematopoiesis for at least 6 months in immunocompromised mice. It attenuates cell differentiation and promotes ex vivo expansion of long term human HSC (LT HSC) at 35 nM in 11 days fed batch cultures. UM171s mechanism is independent of suppression of the aryl hydrocarbon receptor (AHR) like

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