![MELK-IN-1 Size:Contact sales@xcessbio.com for quotation 5S)-5-[di(²H₃)methylcarbamoyl]pyrrolidin-3-yl]sulfanyl}-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3](https://cdn.shopify.com/s/files/1/0389/1897/9723/products/M27770_1636004114.gif?v=1636004116)
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5S)-5-[di(²H₃)methylcarbamoyl]pyrrolidin-3-yl]sulfanyl}-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3
6-diaminohexanamido)butanoic acid
Flumatinib (HHGV678) effectively overcame the drug resistance of certain KIT mutants with activation loop mutations (i
129(31):9594-5
InChi: InChI=1S/C16H12O5/c1-20-11-4-2-9(3-5-11)14-8-13(19)16-12(18)6-10(17)7-15(16)21-14/h2-8
MELK-IN-1 Size:Contact [email protected] for quotation 5S)-5-[di(²H₃)methylcarbamoyl]pyrrolidin-3-yl]sulfanyl}-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3MELK IN 1 is a potent inhibitor of maternal embryonic leucine zipper kinase (MELK) with an IC50 and a Ki of 3 nM and 0. 39 nM, respectively. Product information CAS Number: 2095596 44 2 Molecular Weight: 539. 62 Formula: C31H33N5O4 Chemical Name: methyl 2 hydroxy 3 [({4 [N methyl 2 (4 methylpiperazin 1 yl)acetamido]phenyl}imino)(phenyl)methyl] 1H indole 5 carboxylate Smiles:
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