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Hydroxychloroquine (HCQ) - Autophagy and TLR9 Inhibitor. CAS# 747-36-4 Catalog No.:M60302-10S Tasquinimod

SKU: 49886113334

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Description

Tasquinimod

Impact of a baseline polymorphism on the emergence of resistance to the hepatitis C virus nonstructural protein 5A replication complex inhibitor

Smiles: [Na+]

Go6983 was dosed by IV injection to mice bearing B16BL6 tumors at 22 μg per mouse

5-20 mg/kg once or twice per day to inhibit tumor growth

Hydroxychloroquine (HCQ) - Autophagy and TLR9 Inhibitor. CAS# 747-36-4 Catalog No.:M60302-10S TasquinimodHydroxychloroquine (HCQ), CAS No. 747 36 4, is a potent autophagy inhibitor and TLR9 inhibitor. It prevents lysosomal acidification, thereby interfering with a key step in the autophagic process. In cancer cells, HCQ treatment has been shown to cause increased apoptosis, tumor regression, and delay in tumor recurrence. HCQ was an effective growth inhibitor of human RCC cell lines, inhibiting growth, promoting apoptosis, and effecting cellular

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