VX-770 Size:2mg solid CAS Number: 2072057-18-0

CAS Number: 2072057-18-0

2019 Feb 21

15(1):23-36

15(8):1467-76

LW8 demonstrated strong anti-tumor efficacy in vivo and caused a decrease in HIF-1alpha expression in frozen-tissue immunohistochemical staining

VX-770 Size:2mg solid CAS Number: 2072057-18-0VX 770, is a drug used to treat cystic fibrosis in people with certain mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, who account for 45% cases of cystic fibrosis, and is included in a combination drug, lumacaftor ivacaftor, which is used to treat people with cystic fibrosis who have the F508del mutation in CFTR. Ivacaftor is a "potentiator" of CFTR, meaning it increases the probability that the defective channel