EGFR-IN-7 3-C2-NH-Boc Salubrinal is a selective phosphatase

Salubrinal is a selective phosphatase inhibitor that prevents dephosphorylation of eukaryotic translation initiation factor 2 subunit α (eIF2α)

2017 Aug 18

7(10):e45539

2-Thiazolylamine

Smiles: CC1=CC(=C(C=C1C)C1=CC=C(/C=C2\C(=O)N(N=C\2C)C2C=CC(=CC=2)C(O)=O)O1)[N+]([O-])=O

EGFR-IN-7 3-C2-NH-Boc Salubrinal is a selective phosphataseEGFR IN 7 (compound 34) is a selective and potent EGFR kinase inhibitor extracted from patent WO2019015655A1, has IC50s of 7. 92 nM and 0. 218 nM for EGFR (WT) and EGFR (mutant C797S T790M L858R) respectively, and shows anti tumor activity. Product information CAS Number: 2267329 76 8 Molecular Weight: 694. 60 Formula: C32H41BrN9O2P Chemical Name: 5 bromo N4 [5 (dimethylphosphoryl)quinoxalin 6 yl] N2 {2 methoxy 5 methyl 4 [4 (4 methylpiperazin 1