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PRI-724 - CAS# 1422253-38-0 60101 PubMed PMID: 26515592

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Description

PubMed PMID: 26515592

Schelman WR

2016 Aug 5

4-dinitrophenyl)sulfonyl)piperazin-1-yl)quinoline

2020 Feb 6

PRI-724 - CAS# 1422253-38-0 60101 PubMed PMID: 26515592PRI 724, CAS No. 1422253 38 0, also known as C 82 prodrug ICG 001 analog, is a potent, specific inhibitor of the canonical Wnt signaling pathway in cancer stem cells with potential antineoplastic activity. Wnt signaling pathway inhibitor PRI 724 specifically inhibits the recruiting of beta catenin with its coactivator CBP (the binding protein of the cAMP response element binding protein CREB); together with other transcription factors beta catenin CBP

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