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ABT-888 dihydrochloride inhibits the PARP activity with EC50 of 2 nM in C41 cells
InChi: InChI=1S/C24H20F3N5O/c1-31-12-18(21-22(28)29-13-30-23(21)31)15-5-6-19-16(11-15)7-8-32(19)20(33)10-14-3-2-4-17(9-14)24(25
PubMed PMID: 26082009
PubMed PMID: 23865465
It was also shown that PFI-1 could significantly down-regulate Aurora B kinase
Hypocrellin A - CAS# 77029-83-5 435 ABT-888 dihydrochloride inhibits the PARPHypocrellin A, CAS No. 77029 83 5, a naturally occurring PKC inhibitor, has many biological and pharmacological properties, such as antitumour, antiviral, antibacterial, and antileishmanial activities. Hypocrellin A is a promising photosensitizer for anticancer photodynamic therapy (PDT). Product information CAS Number: 77029 83 5 Molecular Weight: 546. 52 Formula: C30H26O10 Chemical Name: Hypocrellin A Smiles:
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