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β-Naphthoflavone-CH2-OH Catalog No.:M15296-2 CAS Number: 2378261-89-1

SKU: 42342667513

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Description

CAS Number: 2378261-89-1

but not the iron chelator desferal

Solubility: DMSO : 125 mg/mL (216

InChi: InChI=1S/C13H14N8O2/c22-13-10(20-2-1-16-18-20)8-17-21(13)12-7-11(14-9-15-12)19-3-5-23-6-4-19/h1-2

It also upregulates Bax and released cytochrome c from the mitochondria into the cytoplasm

β-Naphthoflavone-CH2-OH Catalog No.:M15296-2 CAS Number: 2378261-89-1Naphthoflavone CH2 OH ( NF CH2 OH) is a ligand for arylhydrocarbon receptor (AhR) E3 ligase. Naphthoflavone CH2 OH can be connected to the ligand for protein by a linker to form PROTACs or SNIPERs (e. g., naphthoflavone JQ1) that recruit the AhR E3 ligase complex by incorporating AhR ligands into chimeric molecules. PROTACs are inducers of ubiquitination mediated degradation of cancer promoting proteins . Product information Molecular Weight: 302. 32

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