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a Novel Hsp90 Inhibitor
InChiKey: KOZAEBHIXYBHKA-FCXQYMQBSA-N
70 and 818 nmol/L
Formula: C25H20N4O2S2
19 mM) Ethanol 1
Topotecan Catalog No.:M9751-2 a Novel Hsp90 InhibitorTopocecan is a semisynthetic derivative of camptothecin with antineoplastic activity. During the S phase of the cell cycle, topotecan selectively stabilizes topoisomerase I DNA covalent complexes, inhibiting religation of topoisomerase I mediated single strand DNA breaks and producing potentially lethal double strand DNA breaks when complexes are encountered by the DNA replication machinery. Camptothecin is a cytotoxic quinoline based alkaloid