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Chemical Name: 3-[2
It exhibits 15-fold selectivity for the BAZ2 bromodomain over the CERC2 bromodomain and >100-fold selectivity over a range of other bromodomains
Displays no antitumor activity in vitro or in vivo
IV or PO) has a T1/2 of 3
BMS-34554 (5 μM) induces a time dependent dephosphorylation of IκBα and p65
Matrine lenib (GS-9876) Chemical Name: 3-[2Matrine (Matridin 15 one) is an alkaloid found in plants from the Sophora genus. It has a variety of pharmacological effects, including anti cancer effects, and action as a kappa opioid receptor and u receptor agonist. Product information CAS Number: 519 02 8 Molecular Weight: 248. 36 Formula: C15H24N2O Synonym: Matridin 15 one NSC 146051 NSC146051 NSC 146051 Chemical Name: (1R, 2R, 9S, 17S) 7, 13 diazatetracyclo[7. 7. 1. 0, . 0, ]heptadecan 6 one
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