Pay in 4 interest-free payments of $32.25 Learn more
Ships within 48 hours · Estimated delivery Aug 2 - Aug 7
Allosteric inhibitors of Bcr-abl-dependent cell proliferation
342(6161):979-83
Pairing of forskolin and KCl increases differentiation of immortalized hippocampal neurons in a CREB Serine 133 phosphorylation-dependent and extracellular-regulated protein kinase-independent manner
5 μM) and displays antitumor activity in vivo
Chemical Name: 6-(4-bromo-2-chlorophenylamino)-7-fluoro-N-(2-hydroxyethoxy)-3-methyl-3H-benzo[d]imidazole-5-carboxamide
PF-CBP1 - CBP/p300 Bromodomain Inhibitor. CAS# 1962928-21-7 Catalog No.:M60313-10S Allosteric inhibitors of Bcr-abl-dependent cellPF CBP1, CAS No. 1962928 21 7, is a potent and selective CBP p300 bromodomain inhibitor (IC50 ~125 nM for CBP and 363 nM for p300). It has >100 fold selectivity for CBP over BRD4, and shows selectivity over a panel of other bromodomains. PF CBP1 reduces LPS induced IL 1, IL 6 and IFN expression in macrophages in vitro. It can also downregulate RGS4 expression in primary cortical neurons in vitro. Product information CAS Number: 1962928 21 7 Molecular