(R)-Simurosertib 118 551 Hydrochloride with only minimal effects on

with only minimal effects on normal HBE cells

94 nM) for the research of triple negative breast cancer (TNBC)

18(4): 528–538

InChiKey: MAVIFAPOMVRMJK-UHFFFAOYSA-N

Smiles: [2H]C1=C(C([2H])=C([2H])C(N)=C1[2H])S(=O)(=O)NC1=NC=CS1

(R)-Simurosertib 118 551 Hydrochloride with only minimal effects on(R) Simurosertib ((R) TAK 931) is the (R) enantiomer of Simurosertib. Simurosertib (TAK 931) is an orally active, selective and ATP competitive cell division cycle 7 (CDC7) kinase inhibitor, with an IC50 of <0. 3 nM . Product information CAS Number: 1330782 69 8 Molecular Weight: 341. 43 Formula: C17H19N5OS Chemical Name: 2 [(2R) 1 azabicyclo[2. 2. 2]octan 2 yl] 6 (5 methyl 1H pyrazol 4 yl) 3H,4H thieno[3,2 d]pyrimidin 4 one Smiles: