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PF-562271 besylate - CAS# 939791-38-5 aminophen metabolite 3-hydroxy-acetaminophen SAR 439859

SKU: 37844724812

4.2
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Description

SAR 439859

Enhanced solubility and functionality of valrubicin (AD-32) against cancer cells upon encapsulation into biocompatible nanoparticles

It is sold under the brand name Q-Roxin in Korea

The combination had greater efficacy than either reparixin or docetaxel alone

InChiKey: MSYMKEYWUWVZQY-RMKNXTFCSA-N

PF-562271 besylate - CAS# 939791-38-5 aminophen metabolite 3-hydroxy-acetaminophen SAR 439859PF 562271 Besylate, also known as PF 562,271 and PF 271, is an orally bioavailable small molecule and ATP competitive focal adhesion kinase (FAK) inhibitor with potential antineoplastic and antiangiogenic activities. PF 562271 inhibits the tyrosine kinase FAK, and to a lesser extent, proline rich tyrosine kinase (PYK2), which may inhibit tumor cell migration, proliferation, and survival. Note: PF 562271 benzesulfonate is also called PF 562271

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