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is a potent MCT inhibitor
Chemical Name: (2S)-2-[(2R)-2-[(R)-[(2S)-1-[(3R
Smiles: OC(=O)C1=CC(=CC=C1N1C[C@H](CC1)OCC1=CC=CC=N1)C(F)(F)F
It demonstrates that high selectivity and potent inhibition of HDAC6 can be achieved through careful choice of linker element only
Formula: C25H34ClFN4O
Vandetanib - CAS# 443913-73-3 CRABP-II Degrader-1 is a potent MCT inhibitorVandetanib is an orally bioavailable 4 anilinoquinazoline. Vandetanib selectively inhibits the tyrosine kinase activity of vascular endothelial growth factor receptor 2 (VEGF2), thereby blocking VEGF stimulated endothelial cell proliferation and migration and reducing tumor vessel permeability. This agent also blocks the tyrosine kinase activity of epidermal growth factor receptor (EGFR), a receptor tyrosine kinase that mediates tumor cell
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