ERK1/2 inhibitor 1 glycerol 3-Benzodioxole-5-carbonyl)piperazin-1-yl]phenyl]ethanone

3-Benzodioxole-5-carbonyl)piperazin-1-yl]phenyl]ethanone

1-100 μM) increase [Ca2+]i in a concentrationdependent and stereoselective manner

InChi: InChI=1S/C14H8N2O8S2/c17-13(18)9-5-7(1-3-11(9)15(21)22)25-26-8-2-4-12(16(23)24)10(6-8)14(19)20/h1-6H

SirReal2 can increase tubulin hyperacetylation in HeLa cells and induces destabilization of the checkpoint protein BubR1

Smiles: CC1N=C2SC=CN2C(=O)C=1CCN1CCC(CC1)=C(C1C=CC(F)=CC=1)C1C=CC(F)=CC=1

ERK1/2 inhibitor 1 glycerol 3-Benzodioxole-5-carbonyl)piperazin-1-yl]phenyl]ethanoneERK1 2 inhibitor 1 is a potent, orally bioavailable ERK1 2 inhibitor, showing 60% inhibition at 1 nM and an IC50 of 3. 0 nM against ERK1 and ERK2, respectively. Product information CAS Number: 2095719 90 5 Molecular Weight: 550. 05 Formula: C29H32ClN5O4 Chemical Name: (2R) 2 (6 {5 chloro 2 [(oxan 4 yl)amino]pyrimidin 4 yl} 1 oxo 2,3 dihydro 1H isoindol 2 yl) N [(1S) 2 hydroxy 1 (3 methylphenyl)ethyl]propanamide Smiles: