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GYKI 52466 dihydrochloride 11573 Smiles: CC(C)NCC(O)COC1=CC=C(CCOC)C=C1

SKU: 35103656640

4.2
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Description

Smiles: CC(C)NCC(O)COC1=CC=C(CCOC)C=C1

Kitagawa Y

9 nM for PKCβI and PKCβII

Protective effects of guggulsterone against colitis are associated with the suppression of TREM-1 and modulation of macrophages

Chronic infusion of β-Amyloid (1-40) into rat cerebroventricle leads to deficit in spatial and non-spatial memory formation

GYKI 52466 dihydrochloride 11573 Smiles: CC(C)NCC(O)COC1=CC=C(CCOC)C=C1GYKI 52466 dihydrochloride is a potent, selective, orally active and non competitive kainate and AMPA activated currents antagonist with IC50s of 7. 5 M and 11 M, respectively. GYKI 52466 dihydrochloride is inactive against N methyl D aspartate (NMDA) or aminobutyric acid responses. GYKI 52466 dihydrochloride ia a muscle relaxant and anticonvulsant agent, and has good blood brain barrier permeability. Product information CAS Number: 2319722 40 0

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