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Ki=112 μM)
suggesting that extensive first-pass metabolism in the liver is the likely reason for its poor bioavailability
with Ki of 5
InChi: InChI=1S/C7H6O2S
CAS Number: 944153-47-3
TPC2-A1-N Catalog No.:M31877-C Ki=112 μM)TPC2 A1 N is a powerful and Ca2+ permeable agonist of two pore channel 2 (TPC2), which plays its role by mimicking the physiological actions of NAADP. TPC2 A1 P reproducibly evokes significant Ca2+ responses from TPC2 (EC50=7. 8 M), and the effect can be blocked by several TPC blockers. TPC2 A1 N can be used to probe different functions of TPC2 channels in intact cells. Product information CAS Number: 136186 07 7 Molecular Weight: 401. 17 Formula: