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It exhibits only peripheral activity since it does not readily cross the blood-brain barrier
Monensin is an ionophore related to the crown ethers with a preference to form complexes with monovalent cations such as: Li+
4-oxadiazol-2-yl]cyclobutyl)-3-phenyl-1
Chemical Name: N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)-4-((4-methylpiperazin-1-yl)methyl)benzamide methanesulfonate
causing general central nervous system depression
Sulbactam Catalog No.:M8108-2 It exhibits only peripheral activitySulbactam, also known as CP 45899, is a lactamase inhibitor. This drug is given in combination with lactam antibiotics to inhibit lactamase, an enzyme produced by bacteria that destroys the antibiotics. Sulbactam is an irreversible inhibitor of lactamase; it binds to the enzyme and does not allow it to degrade the antibiotic. Sulbactam is able to inhibit the most common forms of lactamase but is not able to interact with the AmpC cephalosporinase.
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