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PKC-IN-1 - CAS# 1046787-18-1 size:10mg solid Ionomycin is a Calcium ionophore

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Description

Ionomycin is a Calcium ionophore and an antibiotic produced by Streptomyces conglobatus

(2009) Cell Stem Cell

Epub 2013 Apr 11

increase in extracellular acidification rate

Formula: C14H14ClN3O2S

PKC-IN-1 - CAS# 1046787-18-1 size:10mg solid Ionomycin is a Calcium ionophorePKC IN 1, CAS No. 1046787 18 1, is a potent, ATP competitive and reversible inhibitor of conventional PKC enzymes with Kis of 5. 3 and 10. 4 nM for human PKC and PKC, and IC50s of 2. 3, 8. 1, 7. 6, 25. 6, 57. 5, 314, 808 nM for PKC, PKCI, PKCII, PKC, PKC, PKC mu and PKC, respectively. IC50: 2. 3 nM (Human PKC), 7. 6 nM (Human PKCII), 8. 1 nM (Human PKCI), 25. 6 nM (Human PKC), 57. 5 nM (Human PKC), 314 nM (Human PKC mu), 808 nM (Human PKC) Ki: 5. 3 nM

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