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Tamibarotene - CAS# 94497-51-5 Catalog No.:M10640-10 Chemical Name: 4-[3-bromo-4-ethoxy-5-(4-methylbenzoyl)benzamido]benzoic acid

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Description

Chemical Name: 4-[3-bromo-4-ethoxy-5-(4-methylbenzoyl)benzamido]benzoic acid

Completo G

and potentially other antidiabetic medication

InChi: InChI=1S/C7H10N2OS/c1-2-3-5-4-6(10)9-7(11)8-5/h4H

DMU2139 shows 88 and 133-fold selectivity for CYP1B1 over CYP1A1 and CYP1A2

Tamibarotene - CAS# 94497-51-5 Catalog No.:M10640-10 Chemical Name: 4-[3-bromo-4-ethoxy-5-(4-methylbenzoyl)benzamido]benzoic acidTamibarotene, also known as SY 1425, is an orally active, synthetic retinoid, developed to overcome all trans retinoic acid (ATRA) resistance, with potential antineoplastic activity. As a specific retinoic acid receptor (RAR) alpha beta agonist, tamibarotene is approximately ten times more potent than ATRA in inducing cell differentiation and apoptosis in HL 60 (human promyelocytic leukemia) cell lines in vitro. Due to a lower affinity for cellular

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