Pay in 4 interest-free payments of $16.25 Learn more
Ships within 48 hours · Estimated delivery Aug 4 - Aug 9
Chemical Name: 2-Chloro-N-(4-chloro-3-pyridin-2-ylphenyl)-4-methylsulfonylbenzamide
1446502-11-9
beginning at less than micromolar concentrations
(2012) ACS Chem Neurosci
6-dihydropyridine-3-carboxamide
NI-57 - BRPF Bromodomain Inhibitor. CAS# 1883548-89-7 Catalog No.:M60279-10S Chemical Name: 2-Chloro-N-(4-chloro-3-pyridin-2-ylphenyl)-4-methylsulfonylbenzamideNI 57, CAS No. 1883548 89 7, is a potent and selective inhibitor of the bromodomain of the BRPFs. It binds to BRPF1B with a KD of 31 nM (ITC), to BRPF2 with a KD of 108 nM (ITC) and to BRPF3 KD of 408 nM (ITC). NI 57 is very selective against other non Class IV bromodomains, including the BETs, has minimum 32 fold selectivity against BRD9. It shows accelerated FRAP recovery at 1 M in the BRPF2 FRAP assay preventing binding of full length BRPF2 to
US$ 425.00
US$ 164.50
US$ 40.00
US$ 224.50
US$ 225.00
US$ 175.00
US$ 67500.00
US$ 249.50
US$ 249.50
US$ 114.50
US$ 119.00
US$ 225.00
US$ 225.00