Ki-16425 - CAS# 355025-24-0 pound Library of Histone Demethylase to BRPF2 with a KD

to BRPF2 with a KD of 108 nM (ITC) and to BRPF3 KD of 408 nM (ITC)

NI-57 was used at 10 µM final concentration in vitro and in cellular assays

LY2886721 is under clinical study

InChiKey: KIHYPELVXPAIDH-HNSNBQBZSA-N

PRMT6 and CARM1 (IC50 are 166

Ki-16425 - CAS# 355025-24-0 pound Library of Histone Demethylase to BRPF2 with a KDKi16425, CAS No. 355025 24 0, is a competitive, potent and reversible antagonist to LPA1, LPA2 and LPA3 with Ki of 0. 34 M, 6. 5 M and 0. 93 M, respectively, shows no activity at LPA4, LPA5, LPA6. IC50 value: 0. 3 6. 5 0. 93 uM(Ki, LPA1 2 3) Target: LPA1 2 3 Product information CAS Number: 355025 24 0 Molecular Weight: 474. 96 Formula: C23H23ClN2O5S Chemical Name: 3 ((4 (4 (((1 (2 chlorophenyl)ethoxy)carbonyl)amino) 3 methylisoxazol 5