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K-Ras ligand-Linker Conjugate 2 rcetrapib Chemical Name: L-seryl-L-threonyl-L-seryl-L-glutaminyl-L-lysyl-L-seryl-L-isoleucyl-L-valyl-L-alanyl-L-tyrosyl-L-threonyl-L-methionine

SKU: 30032010086

4.2
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Description

Chemical Name: L-seryl-L-threonyl-L-seryl-L-glutaminyl-L-lysyl-L-seryl-L-isoleucyl-L-valyl-L-alanyl-L-tyrosyl-L-threonyl-L-methionine

b-AP15 induces apoptosis by cathepsin D-dependent caspase-cleavage (IC50 ~0

promethazine and chlorprothixene]

CAS Number: 1640808-39-4

by using an inositol phosphate (IP) accumulation assay

K-Ras ligand-Linker Conjugate 2 rcetrapib Chemical Name: L-seryl-L-threonyl-L-seryl-L-glutaminyl-L-lysyl-L-seryl-L-isoleucyl-L-valyl-L-alanyl-L-tyrosyl-L-threonyl-L-methionineK Ras ligand Linker Conjugate 2 incorporates a ligand for K Ras, and a PROTAC linker, which recruit E3 ligases (such as VHL, CRBN, MDM2, and IAP). K Ras ligand Linker Conjugate 2 can be used in the synthesis of PROTAC K Ras Degrader 1 (HY 129523), which is potent PROTAC K Ras degrader that exhibits 70% degradation efficacy in SW1573 cells. Product information Molecular Weight: 822. 99 Formula: C45H58N8O7 Chemical Name: benzyl (2S) 4 [2 [[(2S, 4R) 4 [2

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