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PHA-848125 - CAS# 802539-81-7 Catalog No.:M10691-10 JAK2 inhibitor AZD1480 inhibits JAK2

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Description

JAK2 inhibitor AZD1480 inhibits JAK2 activation

Formula: C5H11NO2S

Nupercainal hydrochloride

PubMed PMID: 27696405

we temporally name it as MDK-0264

PHA-848125 - CAS# 802539-81-7 Catalog No.:M10691-10 JAK2 inhibitor AZD1480 inhibits JAK2Milciclib, also known as PHA 848125 or PHA 848125AC, is an orally bioavailable inhibitor of cyclin dependent kinases (CDKs) and thropomyosin receptor kinase A (TRKA), with potential antineoplastic activity. CDK2 TRKA inhibitor PHA 848125 AC potently inhibits cyclin dependent kinase 2 (CDK2) and exhibits activity against other CDKs including CDK1 and CDK4, in addition to TRKA. Inhibition of these kinases may result in cell cycle arrest and apoptosis of

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