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InChi: InChI=1S/C21H22N4O2/c1-24(2)11-9-22-20(26)16-8-5-10-25-19(16)23-18-13-15-7-4-3-6-14(15)12-17(18)21(25)27/h3-8
InChiKey: PIPZGJSEDRMUAW-ZKKXXTDSSA-N
InChiKey: ADVPTQAUNPRNPO-REOHCLBHSA-N
CAS Number: 6009-98-9
InChi: InChI=1S/C22H17ClFNO4/c1-13(14-2-4-15(5-3-14)22(27)28)25-21(26)19-12-16(23)6-11-20(19)29-18-9-7-17(24)8-10-18/h2-13H
OG-L002 HCl 2623 InChi: InChI=1S/C21H22N4O2/c1-24(2)11-9-22-20(26)16-8-5-10-25-19(16)23-18-13-15-7-4-3-6-14(15)12-17(18)21(25)27/h3-8OG L002 is a specific and potent inhibitor of lysine (K) specific demethylase 1A (LSD1) with IC50 value of 20 nM . LSD1 is a flavin dependent monoamine oxidase, which can demethylate lysines. LSD1 plays critical roles in oocyte growth, embryogenesis and tissue specific differentiation . OG L002 potently inhibited HSV IE gene expression in both HFF and HeLa cells with IC50 of ~3 M and ~10 M, respectively. OG L002 treatment can potently reduce
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