(S, R, S)-AHPC-PEG3-NH2 Size:Contact [email protected] for quotation MDL-29951 inhibits the human liver

MDL-29951 inhibits the human liver (IC50=2

2-thiazinan-2-yl)-N-[(4-fluorophenyl)methyl]-5-hydroxy-1-methyl-6-oxo-1

it is approved by the Food and Drug Administration for use in combination with ombitasvir

InChi: InChI=1S/C229H345N69O41/c1-7-135(6)181(218(337)297-122-50-89-178(297)216(335)283-108-33-72-161(283)190(309)261-132-180(300)262-157(128-137-54-15-9-16-55-137)206(325)293-118-46-84-173(293)212(331)284-109-37-77-166(284)192(311)265-146(65-26-98-254-223(237)238)185(304)276-158(129-138-56-17-10-18-57-138)207(326)294-119-47-85-174(294)213(332)286-111-39-78-167(286)193(312)266-147(66-27-99-255-224(239)240)186(305)277-160(131-140-60-21-12-22-61-140)209(328)298-123-51-90-179(298)219(338)339)279-187(306)148(67-28-100-256-225(241)242)267-194(313)168-79-40-112-287(168)211(330)172-83-45-117-292(172)205(324)156(125-134(4)5)274-184(303)145(64-25-97-253-222(235)236)264-191(310)165-76-38-110-285(165)214(333)175-86-48-120-295(175)208(327)159(130-139-58-19-11-20-59-139)278-189(308)153(126-136-52-13-8-14-53-136)272-198(317)170-81-42-114-289(170)215(334)177-88-49-121-296(177)217(336)176-87-44-116-291(176)203(322)152(71-32-104-260-229(249)250)271-196(315)163-74-35-106-281(163)201(320)150(69-30-102-258-227(245)246)269-197(316)164-75-36-107-282(164)204(323)155(124-133(2)3)275-188(307)154(127-141-91-93-142(299)94-92-141)273-199(318)169-80-41-113-288(169)210(329)171-82-43-115-290(171)202(321)151(70-31-103-259-228(247)248)270-195(314)162-73-34-105-280(162)200(319)149(68-29-101-257-226(243)244)268-183(302)144(63-24-96-252-221(233)234)263-182(301)143(230)62-23-95-251-220(231)232/h8-22

Plemper RK

(S, R, S)-AHPC-PEG3-NH2 Size:Contact [email protected] for quotation MDL-29951 inhibits the human liver(S,R,S) AHPC PEG3 NH2 is a synthesized E3 ligase ligand linker conjugate that incorporates the (S,R,S) AHPC based VHL ligand and 3 unit PEG linker used in PROTAC technology. Product information CAS Number: 2010159 56 3 Molecular Weight: 619. 77 Formula: C30H45N5O7S Chemical Name: (2S,4R) 1 [(2S) 2 (2 {2 [2 (2 aminoethoxy)ethoxy]ethoxy}acetamido) 3,3 dimethylbutanoyl] 4 hydroxy N {[4 (4 methyl 1,3 thiazol 5 yl)phenyl]methyl}pyrrolidine 2 carboxamide