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21(53):8149-8157
InChiKey: ZPHYPKKFSHAVOE-YZIXBPQXSA-N
2-difluoropropanamide
3 L/kg in rats
951 are approximately 2000-fold selective for the glycine binding site relative to the glutamate recognition sites
Sitagliptin phosphate ine(Oxedrine) 21(53):8149-8157Sitagliptin (INN; previously identified as MK 0431 and sold under the trade name Januvia) is an oral antihyperglycemic (anti diabetic drug) of the dipeptidyl peptidase 4 (DPP 4) inhibitor class. It was developed and is marketed by Merck & Co. This enzyme inhibiting drug is used either alone or in combination with other oral antihyperglycemic agents (such as metformin or a thiazolidinedione) for treatment of diabetes mellitus type 2. The benefit of