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Pomalidomide-PEG4-Ph-NH2 Catalog No.:M13003-10 InChiKey: XUBOMFCQGDBHNK-UHFFFAOYSA-N

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Description

InChiKey: XUBOMFCQGDBHNK-UHFFFAOYSA-N

[1-3] VX-745 (60 nM-20 µM) inhibits IL-6 and VEGF secretion in bone marrow stromal cells (BMSCs)

the structurally similar but ineffective JAK1/2 inhibitors INCB027753 and INCB029843 has no significant effect in any of these assays systems when tested at concentrations up to 10 μM

96 hours) inhibits the growth of A549 cells

and 4-fold higher efficacy as a Ca2+ channel agonist

Pomalidomide-PEG4-Ph-NH2 Catalog No.:M13003-10 InChiKey: XUBOMFCQGDBHNK-UHFFFAOYSA-NPomalidomide PEG4 Ph NH2 is a synthesized E3 ligase ligand linker conjugate that incorporates the Pomalidomide based cereblon ligand and 4 unit PEG linker used in PROTAC technology. Product information CAS Number: 1818885 63 0 Molecular Weight: 540. 56 Formula: C27H32N4O8 Chemical Name: 4 [12 (4 aminophenoxy) 4,7,10 trioxa 1 azadodecan 1 yl] 2 (2,6 dioxopiperidin 3 yl) 2,3 dihydro 1H isoindole 1,3 dione Smiles:

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