AG-636 217903 CAS Number: 882157-88-2

CAS Number: 882157-88-2

selective and cell permeable type I PRMT inhibitor (catalyzes mono- and asymmetric dimethylation of arginine residues) with IC50 of 30 nM

Smiles: CC(=O)O[C@]12[C@H]3[C@@H](OC(=O)C4C=CC=CC=4)[C@](O)(C[C@H]3C34[C@@H]5[C@@H](OC)C1C3N(C[C@@]5(CC[C@@H]4OC)COC)CC)[C@@H](OC)[C@@H]2O

In vitro: Dilute the received ready-to-use iPSC-TSPC cocktail at 1:1000 into your iPSC reprogramming medium to make the iPSC-TSPC media for iPSC induction

5-dihydroxy-4-methoxy-6-methyloxan-2-yl]oxy}-3-iodo-5

AG-636 217903 CAS Number: 882157-88-2AG 636 is a potent, reversible, selective and orally active dihydroorotate dehydrogenase (DHODH) inhibitor with an IC50 of 17 nM. Differential AG 636 activity translated to the in vivo setting, with complete tumor regression observed in a lymphoma model. Dissection of the relationship between uridine availability and response to AG 636 revealed a divergent ability of lymphoma and solid tumor cell lines to survive and grow in the setting of depleted