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Raloxifene 4'-glucuronide 11377 Smiles: CC(C)NC[C@@H](O)COC1=CC=C(CC(N)=O)C=C1

SKU: 23753711407

4.5
USD100.00 USD146.00

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Description

Smiles: CC(C)NC[C@@H](O)COC1=CC=C(CC(N)=O)C=C1

Mixed Lineage Kinase Domain-Like Protein Inhibitor

Chemical Name: (acetyloxy)methyl 2-({2-[2-(5-{6-[(acetyloxy)methoxy]-2

7 inhibitor

InChi: InChI=1S/C9H13N2O2

Raloxifene 4'-glucuronide 11377 Smiles: CC(C)NC[C@@H](O)COC1=CC=C(CC(N)=O)C=C1Raloxifene 4' glucuronide is a primary metabolite of Raloxifene. Raloxifene 4' glucuronide formation is mediated mostly by UGT1A10 and UGT1A8. Raloxifene 4' glucuronide binds to estrogen receptor with an IC50 of 370 M. . Raloxifene is a selective estrogen receptor modulator. Raloxifene activates TGF3 promoter as a full agonist at nanomolar concentrations, and inhibits the estrogen response element containing vitellogenin promoter expression. Product

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